Pathway-based genetic analysis of preterm birth
نویسندگان
چکیده
منابع مشابه
Pathway Analysis of Genetic Factors Associated with Spontaneous Preterm Birth and Pre-Labor Preterm Rupture of Membranes
BACKGROUND Pre-term birth (PTB) remains the leading cause of infant mortality and morbidity. Its etiology is multifactorial, with a strong genetic component. Genetic predisposition for the two subtypes, spontaneous PTB with intact membranes (sPTB) and preterm prelabor rapture of membranes (PPROM), and differences between them, have not yet been systematically summarised. METHODS AND FINDINGS ...
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The high prevalence, increasing frequency, and adverse outcomes for mothers and infants of preterm birth have led to heightened awareness of this public health concern. The causes of preterm birth are likely to be multifactorial, with genetic, infectious, nutritional, behavioral, and other environmental contributors. Because of important differences in the physiology of human pregnancy and that...
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AIM Our goal wasto produce a field synopsis of genetic associations with preterm birth and to set up a publicly available online database summarizing the data. METHODS We performed a systematic review and meta-analyses to identify genetic associations with preterm birth. We have set up a publicly available online database of genetic association data on preterm birth called PTBGene (http://ric...
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OBJECTIVE The objective of this study was to compare the cost-effectiveness of 9 strategies for the management of threatened preterm labor. STUDY DESIGN We derived 6 management options from the literature. These were (1) to treat all women with tocolytics and corticosteroids ("treat all"); (2) to treat all women while awaiting results of the "traditional" fetal fibronectin test results, then ...
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ژورنال
عنوان ژورنال: Genomics
سال: 2013
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2012.12.005